Cellular traffic jams inside a fruit fly embryo might sound like a minor detail, but new work suggests they help flip a fundamental genetic switch. As cells pack together during early development, ...

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This ...

Biochemical ‘DNA methylation’ marks are found across the genome in vertebrate animals, but in the early embryos of placental mammals, such as mice and humans, they are largely erased in a ‘system ...

This work delineates how Setd2-mediated epigenetic reprogramming overcomes developmental barriers in cloned embryos. Comparative analysis revealed that SCNT embryos exhibit excessive H3K4me3 and ...

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves. A new study from the University of Bonn offers an explanation for ...

Building upon previous work, researchers at the Icahn School of Medicine at Mount Sinai identified cells in the embryos of mice that are precursors to blood stem cells or hematopoietic stem/progenitor ...

2007 was the year scientists discovered a method of stem-cell research that could eliminate the need for destroying embryos. It was also a year when a number of initiatives got started to recognize ...

Researchers have shown that cloned embryos undergo complete nuclear reprogramming and resemble fertilized embryos. The report, appearing in the December 6 issue of Proceedings of the National Academy ...

One of the biggest holy grails in biology involves finding a means to generate pluripotent and infinitely replicating stem cells without generating an embryo. One Japanese team presented some potent ...